{"id":1800,"date":"2024-02-12T22:37:11","date_gmt":"2024-02-12T22:37:11","guid":{"rendered":"https:\/\/myneuronews.tempurl.host\/?p=1800"},"modified":"2025-04-27T10:52:20","modified_gmt":"2025-04-27T10:52:20","slug":"post-traumatic-headache-treatment-overview","status":"publish","type":"post","link":"https:\/\/beyondtheimpact.net\/?p=1800","title":{"rendered":"Post-traumatic headache: Treatment Overview"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\"><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">Pharmacological Interventions for PTH<\/h4>\n\n\n\n<p>Multiple pharmacological options are available for managing post-traumatic headaches (PTH). Common choices include nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen for mild to moderate headache relief, with paracetamol also being an effective option.<\/p>\n\n\n\n<p>Research has explored the effect of early administration of ibuprofen and acetaminophen in children and adolescents with concussion, finding no significant impact on headache resolution seven days post-concussion. Although these non-opioid pain relievers are recommended for short-term relief, their long-term usage requires caution due to potential risks.<\/p>\n\n\n\n<p>Antiepileptic drugs and tricyclic antidepressants (TCAs) have shown benefits in managing PTH symptoms, with studies indicating significant symptom improvement over time. Gabapentin and TCAs, in particular, have been associated with both immediate and sustained symptom relief, despite the initial higher symptom scores in medicated patients.<\/p>\n\n\n\n<p>For chronic PTH following mTBI, retrospective studies have demonstrated the effectiveness of prophylactic medications, with topiramate showing a notable decrease in headache frequency. Triptan-class medications have also been effective, especially for blast and non-blast-related PTH, highlighting the varied response based on the headache&#8217;s etiology.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Repetitive Transcranial Magnetic Stimulation (rTMS)<\/h4>\n\n\n\n<p>rTMS, a non-invasive neurostimulation method, has shown promise in treating PTH and post-concussion depression, with several studies reporting positive outcomes despite limitations in sample size and methodology.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Neutralizing Prismatic Lenses<\/h4>\n\n\n\n<p>For patients with vertical heterophoria (VH), neutralizing prismatic lenses have significantly reduced headache, dizziness, and anxiety symptoms, suggesting an effective treatment route for PTH associated with VH.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Peripheral Nerve Surgery<\/h4>\n\n\n\n<p>Peripheral nerve surgery has been presented as a viable option for patients with persistent PTH, with studies showing substantial pain reduction and successful outcomes in a significant proportion of patients undergoing occipital nerve surgery.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Botulinum Toxin<\/h4>\n\n\n\n<p>Botulinum toxin injections have been reported to effectively alleviate chronic tension-type PTHs, showing significant improvement in headache symptoms, cognitive function, and quality of life in patients with persistent symptoms post-TBI.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><div class=\"pcrstb-wrap\"><table><thead><tr><th><strong>Treatment Type<\/strong><\/th><th><strong>Application<\/strong><\/th><th><strong>Key Findings<\/strong><\/th><\/tr><\/thead><tbody><tr><td><strong>Pharmacological<\/strong><\/td><td>NSAIDs (e.g., ibuprofen, naproxen), Paracetamol<\/td><td>Commonly used for mild to moderate headaches. No significant impact on headache resolution seven days post-concussion in a study on children and adolescents.<\/td><\/tr><tr><td><\/td><td>Antiepileptic drugs, Tricyclic antidepressants (TCAs)<\/td><td>Showed significant symptom improvement over time; gabapentin and TCAs specifically linked to immediate and sustained symptom relief.<\/td><\/tr><tr><td><\/td><td>Prophylactic medications (e.g., topiramate, triptan-class medications)<\/td><td>Effective in reducing headache frequency, especially for chronic PTH. Triptan-based medications were notably effective for both blast and non-blast PTH.<\/td><\/tr><tr><td><strong>Non-Pharmacological<\/strong><\/td><td>Repetitive Transcranial Magnetic Stimulation (rTMS)<\/td><td>Showed promising results in treating PTH and post-concussion depression, with positive outcomes in several small studies.<\/td><\/tr><tr><td><\/td><td>Neutralizing Prismatic Lenses<\/td><td>Effective in reducing symptoms of headache, dizziness, and anxiety in patients with vertical heterophoria (VH).<\/td><\/tr><tr><td><strong>Surgical and Interventional<\/strong><\/td><td>Peripheral Nerve Surgery<\/td><td>Resulted in substantial pain reduction and successful outcomes in a significant number of patients with persistent PTH.<\/td><\/tr><tr><td><\/td><td>Botulinum Toxin<\/td><td>Effective in alleviating chronic tension-type PTHs, with improvements noted in headache symptoms, cognitive function, and quality of life.<\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n\n\n\n<p>This table provides an overview of the diverse treatment landscape for PTH, highlighting the importance of individualized treatment strategies based on the patient&#8217;s specific symptoms and the underlying cause of their headaches.<\/p>\n\n\n\n<p><strong>Literature &#8211; further reading:<\/strong><\/p>\n\n\n\n<p>Cushman D.M., Borowski L., Hansen C., Hendrick J., Bushman T., Teramoto M. Gabapentin and Tricyclics in the Treatment of Post-Concussive Headache.; a Retrospective Cohort Study.&nbsp;<em>Headache.&nbsp;<\/em>2019;59:371\u2013382. doi:&nbsp;10.1111\/head.13451.&nbsp;[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30451286\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.1111%2Fhead.13451\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]&nbsp;[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Headache&amp;title=Gabapentin+and+Tricyclics+in+the+Treatment+of+Post-Concussive+Headache.;+a+Retrospective+Cohort+Study&amp;author=D.M.+Cushman&amp;author=L.+Borowski&amp;author=C.+Hansen&amp;author=J.+Hendrick&amp;author=T.+Bushman&amp;volume=59&amp;publication_year=2019&amp;pages=371-382&amp;pmid=30451286&amp;doi=10.1111\/head.13451&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Erickson J.C. Treatment outcomes of chronic post-traumatic headaches after mild head trauma in US soldiers: An observational study.\u00a0<em>Headache.\u00a0<\/em>2011;51:932\u2013944. doi:\u00a010.1111\/j.1526-4610.2011.01909.x.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21592097\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.1111%2Fj.1526-4610.2011.01909.x\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Headache&amp;title=Treatment+outcomes+of+chronic+post-traumatic+headaches+after+mild+head+trauma+in+US+soldiers:+An+observational+study&amp;author=J.C.+Erickson&amp;volume=51&amp;publication_year=2011&amp;pages=932-944&amp;pmid=21592097&amp;doi=10.1111\/j.1526-4610.2011.01909.x&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Mollica A., Safavifar F., Fralick M., Giacobbe P., Lipsman N., Burke M.J. Transcranial Magnetic Stimulation for the Treatment of Concussion: A Systematic Review.\u00a0<em>Neuromodulation.\u00a0<\/em>2021;24:803\u2013812. doi:\u00a010.1111\/ner.13319.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33184973\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.1111%2Fner.13319\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Neuromodulation&amp;title=Transcranial+Magnetic+Stimulation+for+the+Treatment+of+Concussion:+A+Systematic+Review&amp;author=A.+Mollica&amp;author=F.+Safavifar&amp;author=M.+Fralick&amp;author=P.+Giacobbe&amp;author=N.+Lipsman&amp;volume=24&amp;publication_year=2021&amp;pages=803-812&amp;pmid=33184973&amp;doi=10.1111\/ner.13319&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Rosner M.S., Feinberg D.L., Doble J.E., Rosner A.J. Treatment of vertical heterophoria ameliorates persistent post-concussive symptoms: A retrospective analysis utilizing a multi-faceted assessment battery.\u00a0<em>Brain Inj.\u00a0<\/em>2016;30:311\u2013317. doi:\u00a010.3109\/02699052.2015.1113564.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26829465\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.3109%2F02699052.2015.1113564\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Brain+Inj.&amp;title=Treatment+of+vertical+heterophoria+ameliorates+persistent+post-concussive+symptoms:+A+retrospective+analysis+utilizing+a+multi-faceted+assessment+battery&amp;author=M.S.+Rosner&amp;author=D.L.+Feinberg&amp;author=J.E.+Doble&amp;author=A.J.+Rosner&amp;volume=30&amp;publication_year=2016&amp;pages=311-317&amp;pmid=26829465&amp;doi=10.3109\/02699052.2015.1113564&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Lippert-Gr\u00fcner M. Botulinum toxin in the treatment of post-traumatic headache-case study.\u00a0<em>Neurol. Neurochir. Pol.\u00a0<\/em>2012;46:591\u2013594. doi:\u00a010.5114\/ninp.2012.32109.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23319227\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.5114%2Fninp.2012.32109\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Neurol.+Neurochir.+Pol.&amp;title=Botulinum+toxin+in+the+treatment+of+post-traumatic+headache-case+study&amp;author=M.+Lippert-Gr%C3%BCner&amp;volume=46&amp;publication_year=2012&amp;pages=591-594&amp;pmid=23319227&amp;doi=10.5114\/ninp.2012.32109&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Yerry J.A., Kuehn D., Finkel A.G. Onabotulinum toxin a for the treatment of headache in service members with a history of mild traumatic brain injury: A cohort study.\u00a0<em>Headache.\u00a0<\/em>2015;55:395\u2013406. doi:\u00a010.1111\/head.12495.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25644249\">PubMed<\/a>] [<a href=\"https:\/\/doi.org\/10.1111%2Fhead.12495\" target=\"_blank\" rel=\"noreferrer noopener\">CrossRef<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Headache&amp;title=Onabotulinum+toxin+a+for+the+treatment+of+headache+in+service+members+with+a+history+of+mild+traumatic+brain+injury:+A+cohort+study&amp;author=J.A.+Yerry&amp;author=D.+Kuehn&amp;author=A.G.+Finkel&amp;volume=55&amp;publication_year=2015&amp;pages=395-406&amp;pmid=25644249&amp;doi=10.1111\/head.12495&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>Klein S.K., Brown C.B., Ostrowski-Delahanty S., Bruckman D., Victorio M.C. Identifying Migraine Phenotype Post Traumatic Headache (MPTH) to Guide Overall Recovery From Traumatic Brain Injury.\u00a0<em>J. Child Neurol.\u00a0<\/em>:2022.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35656769\">PubMed<\/a>]\u00a0[<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=J.+Child+Neurol.&amp;title=Identifying+Migraine+Phenotype+Post+Traumatic+Headache+(MPTH)+to+Guide+Overall+Recovery+From+Traumatic+Brain+Injury&amp;author=S.K.+Klein&amp;author=C.B.+Brown&amp;author=S.+Ostrowski-Delahanty&amp;author=D.+Bruckman&amp;author=M.C.+Victorio&amp;pages=2022&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the management of post-traumatic headaches (PTH), a multifaceted approach is essential due to the complex nature of the condition and the variability in patient response to treatment. Pharmacological treatments, such as NSAIDs and paracetamol, offer initial relief for mild to moderate headaches, while antiepileptic drugs and tricyclic antidepressants have been shown to provide significant improvements over time. Notably, the effectiveness of prophylactic medications like topiramate and triptan-class medications underscores the tailored approach needed in treating chronic PTH, especially when considering the etiology of the headache, whether related to blast injuries or not.<\/p>\n<p>Beyond pharmacology, non-invasive interventions such as repetitive transcranial magnetic stimulation (rTMS) have emerged as promising options for addressing both PTH and associated depressive symptoms, highlighting the interconnectedness of post-concussion symptomatology. Similarly, the application of neutralizing prismatic lenses for patients with vertical heterophoria (VH) has demonstrated significant reductions in headache, dizziness, and anxiety, offering a novel avenue for symptom management.<\/p>\n<p>For cases resistant to conventional therapies, surgical interventions like peripheral nerve surgery present a viable option, with substantial evidence supporting its efficacy in reducing headache pain and improving patient outcomes. Furthermore, the use of botulinum toxin has been reported to effectively alleviate chronic tension-type PTHs, providing relief when other treatments have failed.<\/p>\n<p>This diverse treatment landscape emphasizes the importance of a personalized and comprehensive approach in the management of PTH, incorporating both traditional pharmacological treatments and innovative therapeutic modalities to address the unique needs of each patient.<\/p>\n","protected":false},"author":2,"featured_media":1765,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[26,47],"tags":[19,40],"class_list":["post-1800","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-professionals","category-post-traumatic-headache","tag-mtbi","tag-post-traumatic-headache"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Post-traumatic headache: Treatment Overview - Beyond the Impact<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondtheimpact.net\/?p=1800\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Post-traumatic headache: Treatment Overview - Beyond the Impact\" \/>\n<meta property=\"og:description\" content=\"In the management of post-traumatic headaches (PTH), a multifaceted approach is essential due to the complex nature of the condition and the variability in patient response to treatment. Pharmacological treatments, such as NSAIDs and paracetamol, offer initial relief for mild to moderate headaches, while antiepileptic drugs and tricyclic antidepressants have been shown to provide significant improvements over time. Notably, the effectiveness of prophylactic medications like topiramate and triptan-class medications underscores the tailored approach needed in treating chronic PTH, especially when considering the etiology of the headache, whether related to blast injuries or not. Beyond pharmacology, non-invasive interventions such as repetitive transcranial magnetic stimulation (rTMS) have emerged as promising options for addressing both PTH and associated depressive symptoms, highlighting the interconnectedness of post-concussion symptomatology. Similarly, the application of neutralizing prismatic lenses for patients with vertical heterophoria (VH) has demonstrated significant reductions in headache, dizziness, and anxiety, offering a novel avenue for symptom management. For cases resistant to conventional therapies, surgical interventions like peripheral nerve surgery present a viable option, with substantial evidence supporting its efficacy in reducing headache pain and improving patient outcomes. Furthermore, the use of botulinum toxin has been reported to effectively alleviate chronic tension-type PTHs, providing relief when other treatments have failed. 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Beyond the Impact","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/beyondtheimpact.net\/?p=1800","og_locale":"en_US","og_type":"article","og_title":"Post-traumatic headache: Treatment Overview - Beyond the Impact","og_description":"In the management of post-traumatic headaches (PTH), a multifaceted approach is essential due to the complex nature of the condition and the variability in patient response to treatment. Pharmacological treatments, such as NSAIDs and paracetamol, offer initial relief for mild to moderate headaches, while antiepileptic drugs and tricyclic antidepressants have been shown to provide significant improvements over time. Notably, the effectiveness of prophylactic medications like topiramate and triptan-class medications underscores the tailored approach needed in treating chronic PTH, especially when considering the etiology of the headache, whether related to blast injuries or not. Beyond pharmacology, non-invasive interventions such as repetitive transcranial magnetic stimulation (rTMS) have emerged as promising options for addressing both PTH and associated depressive symptoms, highlighting the interconnectedness of post-concussion symptomatology. Similarly, the application of neutralizing prismatic lenses for patients with vertical heterophoria (VH) has demonstrated significant reductions in headache, dizziness, and anxiety, offering a novel avenue for symptom management. For cases resistant to conventional therapies, surgical interventions like peripheral nerve surgery present a viable option, with substantial evidence supporting its efficacy in reducing headache pain and improving patient outcomes. Furthermore, the use of botulinum toxin has been reported to effectively alleviate chronic tension-type PTHs, providing relief when other treatments have failed. This diverse treatment landscape emphasizes the importance of a personalized and comprehensive approach in the management of PTH, incorporating both traditional pharmacological treatments and innovative therapeutic modalities to address the unique needs of each patient.","og_url":"https:\/\/beyondtheimpact.net\/?p=1800","og_site_name":"Beyond the Impact","article_published_time":"2024-02-12T22:37:11+00:00","article_modified_time":"2025-04-27T10:52:20+00:00","og_image":[{"width":1280,"height":1280,"url":"https:\/\/beyondtheimpact.net\/wp-content\/uploads\/2024\/02\/mri-782457_1280.jpg","type":"image\/jpeg"}],"author":"Dr Ioannis Mavroudis","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Dr Ioannis Mavroudis","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/beyondtheimpact.net\/?p=1800#article","isPartOf":{"@id":"https:\/\/beyondtheimpact.net\/?p=1800"},"author":{"name":"Dr Ioannis Mavroudis","@id":"https:\/\/beyondtheimpact.net\/#\/schema\/person\/1ae68bbf93b4c1d993f388d942a93c4b"},"headline":"Post-traumatic headache: Treatment Overview","datePublished":"2024-02-12T22:37:11+00:00","dateModified":"2025-04-27T10:52:20+00:00","mainEntityOfPage":{"@id":"https:\/\/beyondtheimpact.net\/?p=1800"},"wordCount":736,"commentCount":0,"publisher":{"@id":"https:\/\/beyondtheimpact.net\/#organization"},"image":{"@id":"https:\/\/beyondtheimpact.net\/?p=1800#primaryimage"},"thumbnailUrl":"https:\/\/beyondtheimpact.net\/wp-content\/uploads\/2024\/02\/mri-782457_1280.jpg","keywords":["mTBI","post-traumatic headache"],"articleSection":["Medical professionals","Post traumatic headache"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/beyondtheimpact.net\/?p=1800#respond"]}]},{"@type":"WebPage","@id":"https:\/\/beyondtheimpact.net\/?p=1800","url":"https:\/\/beyondtheimpact.net\/?p=1800","name":"Post-traumatic headache: Treatment Overview - 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